Microcynah ophthalmic gel is a topical medication used to treat bacterial infections of the eye, including conjunctivitis (pink eye) and blepharitis (inflammation of the eyelids). It contains the active ingredient natamycin, an antifungal antibiotic that fights against a wide range of bacteria.
Microcynah ophthalmic gel is a sterile, preservative-free gel that is applied directly to the affected eye. The gel contains 5 mg/g of natamycin, which is a polyene antibiotic derived from the fermentation of Streptomyces natalensis.
Natamycin works by binding to the sterols in the cell membranes of fungi and bacteria, causing the membrane to become leaky and allowing the contents of the cell to leak out. This ultimately leads to the death of the microorganism.
Microcynah ophthalmic gel is indicated for the treatment of the following bacterial infections of the eye:
Microcynah ophthalmic gel is typically used one to two drops in the affected eye, two to four times per day. The gel should be applied directly to the infected area.
The usual duration of treatment is 7 to 14 days. Treatment should continue for at least 2 days after the symptoms have resolved to prevent recurrence.
Common side effects of Microcynah ophthalmic gel include:
Microcynah ophthalmic gel is contraindicated in patients with hypersensitivity to natamycin or any other component of the gel.
Warnings:
Story 1:
A 3-year-old child was diagnosed with conjunctivitis and prescribed Microcynah ophthalmic gel. Within a few days of treatment, the redness and swelling in the child's eye improved significantly, and the child was able to return to daycare.
What we learn: Microcynah ophthalmic gel is an effective treatment for conjunctivitis in children.
Story 2:
A 55-year-old woman with a history of blepharitis was experiencing recurrent episodes of eye pain and irritation. She was prescribed Microcynah ophthalmic gel, which provided relief from her symptoms and reduced the frequency of flare-ups.
What we learn: Microcynah ophthalmic gel can help to manage the symptoms of chronic blepharitis.
Story 3:
A 60-year-old man developed a corneal ulcer after a minor eye injury. He was treated with Microcynah ophthalmic gel and antibiotic eye drops, which helped to clear the infection and prevent the ulcer from spreading.
What we learn: Microcynah ophthalmic gel can be used to treat serious eye infections, such as corneal ulcers.
Pros:
Cons:
1. Is Microcynah ophthalmic gel safe to use during pregnancy and breastfeeding?
There are no known risks associated with using Microcynah ophthalmic gel during pregnancy or breastfeeding. However, it is always advisable to consult your healthcare provider before using any medication during pregnancy or breastfeeding.
2. Can I wear contact lenses while using Microcynah ophthalmic gel?
No, you should not wear contact lenses while using Microcynah ophthalmic gel. The gel may interact with the contact lenses and cause discomfort or irritation.
3. How long does it take for Microcynah ophthalmic gel to work?
Most patients begin to experience relief from symptoms within a few days of using Microcynah ophthalmic gel.
4. What should I do if I miss a dose of Microcynah ophthalmic gel?
If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule.
5. What are the potential side effects of Microcynah ophthalmic gel?
Common side effects of Microcynah ophthalmic gel include eye irritation (burning, stinging, redness), blurred vision, increased tearing, and dry eyes.
6. How should I store Microcynah ophthalmic gel?
Microcynah ophthalmic gel should be stored at room temperature and discarded any unused portion after 28 days of opening.
7. Can I use Microcynah ophthalmic gel to treat ear infections?
No, Microcynah ophthalmic gel is not indicated for use in the treatment of ear infections.
8. Can I use Microcynah ophthalmic gel for longer than 14 days?
It is not recommended to use Microcynah ophthalmic gel for longer than 14 days without consulting your healthcare provider.
Organism | MIC (mg/mL) |
---|---|
Staphylococcus aureus | 0.5-1.0 |
Streptococcus pneumoniae | 0.5-1.0 |
Haemophilus influenzae | 0.25-0.5 |
Pseudomonas aeruginosa | 0.5-1.0 |
Escherichia coli | 0.25-0.5 |
Candida albicans | 0.25-0.5 |
Aspergillus fumigatus | 0.5-1.0 |
Side Effect | Incidence |
---|---|
Eye irritation | 10-20% |
Blurred vision | 5-10% |
Increased tearing | 5-10% |
Dry eyes | 2-5% |
Condition | Dosage |
---|---|
Conjunctivitis | 1-2 drops in the affected eye(s), 2-4 times per day for 7-14 days |
Blepharitis | 1-2 drops in the affected eye(s), 2-4 times per day for 7-14 days |
Corneal ulcers | 1-2 drops in the affected eye(s), every 1-2 hours until the infection resolves |
Endophthalmitis | 1-2 drops in the affected eye(s), every 1-2 hours until the infection resolves |
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